Thermal ablation of liver malignancies

PhD defence by Jeanett Klubien

Assessment Committee

Associate professor Martin Hylleholt Sillesen, Department of Clinical Medicine, University of Copenhagen (Chairperson)
Associate professor Gerda Elisabeth Villadsen, Aarhus University Hospital
Dr Åsmund Avdem Fretland, Oslo University Hospital

Supervisors

Associate Professor Hans-Christian L Pommergaard
Susanne Dam Poulsen
Associate Professor Jens Georg Hillingsø
Peter Nørgaard Larsen
Professor Jacob Rosenberg

Department

Department of Clinical Medicine

Graduate Programme

Clinical Cancer Research

Place

Building: Opgang 3, Room: 10. sal, Inge Lehmanns Vej 7, 2100 København Ø​​​

Email address to gain access to the thesis: jeanettklubien@gmail.com.
You will either receive a copy of the thesis or be informed where you can read a physical copy.
Recipients of copies of the thesis are not allowed to share or distribute it due to copyright compliance.

Short description of the thesis

Globally, liver malignancies are a major cause of cancer-related morbidity and mortality, and treatment strategies continue to evolve. This thesis investigates thermal ablation for hepatocellular carcinoma and liver metastases across different clinical settings. The studies examine technique efficacy, complications, long-term outcomes, and procedural approaches. Collectively, the findings demonstrate high technique efficacy and low morbidity, while highlighting the importance of tumor burden, patient characteristics, and recurrence for long-term outcomes. The findings support the evolving role of ablation as a minimally invasive treatment for liver malignancies.