PhD defence by Mads Damsgaard Wewer

Mechanisms, Management and Malignancies in Inflammatory Bowel Disease - Fibroblast Characterisation and Prognosis in Population-Based Cohorts

Assessment Committee:
Professor Palle Bekker Jeppesen, Department of Clinical Medicine, University of Copenhagen (Chairperson)
Professor Marte Lie Høivik, Oslo University hospital and University of Olso
Associate professor Azucena Salas, Inflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona

Supervisors:
Clinical Professor Johan  Burisch
Professor Flemming Bendtsen
Professor William Winston Agace, Clinical Professor Jakob Benedict Seidelin,

Department:
Department of Clinical Medicine

Graduate Programme:
Immunology and Infectious Diseases

Place:
Hvidovre Hospital, Room: Aud 3+4, Kettegård Alle 36, 2650

Email address to gain access to the thesis: madswewer@gmail.com 
You will either receive a copy of the thesis or be informed where you can read a physical copy.
Recipients of copies of the thesis are not allowed to share or distribute it due to copyright compliance.

Short description of the thesis:
Inflammatory bowel disease, including Crohn’s disease and ulcerative colitis, is a lifelong condition with highly variable outcomes. Some patients have mild disease, while others require advanced medical therapy, surgery, or face rare but serious complications such as cancer. This PhD thesis investigates how IBD develops and progresses by combining basic science studies of intestinal tissue with large-scale population-based data. The work explores disease mechanisms, long-term treatment patterns, surgery, and cancer risk. Together, the findings aim to improve our understanding of IBD and support more informed decisions for patients and clinicians.