Multimodal Diagnostics in Idiopathic Intracranial Hypertension

Multimodal Diagnostics in Idiopathic Intracranial Hypertension

PhD defence by Elisabeth Arnberg Wibroe

Assessment Committee

Professor Miriam Kolko, Department of Drug Design and Pharmacology, University of Copenhagen (Chairperson)
Professor Toke Bek, Aarhus University
Professor Susan Mollan, Queens University

Supervisors

Professor Steffen Hamann
Rigmor Højland Jensen

Department

Department of Clinical Medicine

Graduate Programme

Neuroscience

Place

Building: 7, Room: Auditurium C, Valdemar Hansens Vej 6, 2600 Glostrup

Email address to gain access to the thesis: elisabeth.arnberg@gmail.com.
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Short description of the thesis

Idiopathic intracranial hypertension (IIH) is a potentially disabling disorder characterized by elevated intracranial pressure in the absence of an identifiable cause. IIH poses significant diagnostic challenges, as diagnosis relies largely on invasive measurements and heterogeneous clinical findings. We aimed to advance the multimodal diagnostic assessment of suspected IIH by integrating biochemical, structural, and physiological biomarkers. We focused on cerebrospinal fluid characteristics, optic nerve head morphology, and retinal vessel dynamics to support more individualized and less invasive patient care.