Independent Research Fund Denmark funds 27 research projects at SUND

This year, 27 projects based at the Faculty of Health and Medical Sciences receive funding from the Independent Research Fund Denmark under the call “DFF-Research Project 1”. 

The new projects cover a great variety of disciplines within the health and medical sciences, and the researchers will investigate child obesity, the relation between vira and Parkinson’s, compare the microbiomes of Neanderthals and modern human beings, develop methods for treating brain tumor, and many other subjects. 

Find the project descriptions at DFF’s website https://dff.dk/hvad-har-vi-stoettet/se-oversigt-over-stoettet-forskning/  

Congratulations to: 

From BMI 

• Alicia Lundby: Deconvolution of the Heartbeat: Spatially Resolved Profiling of Cells and Proteins of the Human Conduction System, 3.164.753 DKK. 
• Julien Bruno Emile Ochala: Rejuvenating myosin super-relaxation in the failing heart, 3.163.773 DKK. 
• Jens Juul Holst: Establishing physiological and translational models to determine the physiological relevance of intestinal gluconeogenesis, 2.789.104 DKK. 
• Signe Sørensen Torekov: Quantifying Hypothalamic Incretin Sensing and Resistance in Obesity: A randomized crossover neuroimaging infusion study, 2.974.193 DKK. 

From BRIC 

• Shohreh Navikas: Mitochondrial targeted therapy in Parkinson’s Disease, 3.166.792 DKK. 

From CBMR 

• Torben Hansen: Translational insights into the proteomic landscape of obesity and cardiometabolic risk in youth, 3.161.058 DKK. 
• Jonas Thue Treebak: Defining the role of Arg-specific ADP ribosylation by ARTC1 for skeletal muscle insulin action, 3.142.555 DKK. 

From CTN 

• Hajime Hirase: Tonic regulation of cerebral blood flow by neuron-glia interactions: from natural brain states to depression, 3.167.909 DKK. 
• Verena Untiet: Astrocytic GABA release drives tonic and phasic inhibition in cortical networks in health and disease, 3.167.909 DKK. 

From GLOBE 

• Hannes Schroeder: BONECODE: Decoding Ancestry and Technology in Early Mesolithic Bone Artefacts from Denmark, 3.166.540 DKK. 
• Ainara Sistiaga: The last Neanderthals: DEciphering Microbiome Influence on Subsistence and Extinction (DEMISE), 3.167.581 DKK. 
• Jazmin Ramos Madrigal: Reconstructing the chronology of selection during maize domestication through genotype imputation of ancient genomes, 3.167.185 DKK. 
• Hannes Schroeder: Fermented Pasts: Recovering Lost Yeast and Microbial Diversity of Beer Brewing Through Ancient Metagenomics, 3.163.588 DKK. 

From ICMM 

• Andrew Blackford: DDIAS is a novel mitotic DNA damage response gene mutated in a neurodevelopmental disorder, 3.154.695 DKK. 

From IF 

• Camilla Foged: Decoding Coexisting Particle Populations in Lipid Nanoparticles for Enhanced mRNA Delivery, 3.037.281 DKK. 
• Christian Janfelt: Development and application of mass spectrometry imaging to reveal localization of peptide drugs in the digestive tract upon oral administration, 3.164.958 DKK. 

From IFSV 

• Zorana Jovanovic Andersen: Unveiling the benefits of Cleaner Air on Lung health in DenMark (CALM), 3.168.000 DKK. 

From ILF 

• Bente Flensborg Frølund: Discovery of first-in-class covalent allosteric modulators for CaMKIIb – a brain relevant kinase, 3.163.939 DKK. 
• Lennart Bunch: A First Selective Orthosteric Agonist PET Tracer for the mGlu2 Receptor, 3.164.364 DKK. 
• Umberto Maria Battisti: Development of Astatine-211 Labeled Tetrazines for Pretargeted Alpha Therapy in the Brain (Brain PretAt), 3.164.180 DKK. 
• Stephan Alexander Pless: Optimization of de novo designed miniproteins for therapeutic application, 3.166.744 DKK. 

From IN 

• Nanna MacAulay: Crossing the first barrier – identification of the choroid plexus basolateral transport mechanisms initiating CSF secretion, 3.168.000 DKK. 
• Ole Kiehn: Reframing basal ganglia circuitry control of locomotion and therapeutic avenues for restoration of gait disturbances in Parkinson’s, 3.165.181 DKK. 
• Martin Fredensborg Rath: Circadian rhythms in the brain: Can 24h rhythmic infusion of glucocorticoids restore local brain clocks to counteract depressive behaviour in a rodent model? 3.167.980 DKK. 
• Claire Francesca Meehan: Shining a light on inhibitory control in Amyotrophic Lateral Sclerosis: The elusive chandelier cell, 3.168.000 DKK. 

From ISIM 

• Ali El-Salanti: The role of onco-fetal Chondroitin sulfate in tumor immune evasion, 3.162.836 DKK. 

From IVH 

• Søren Skov: A novel pathway regulates surface expression of the immune-stimulatory CD137 Ligand on influenza infected cells – what is the zoonotic implication and therapeutic potential? 3.163.216 DKK.