Advanced Methods for the Analysis of Protein Disease Mechanisms – University of Copenhagen

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Advanced Methods for the Analysis of Protein Disease Mechanisms


Biology in general and clinical biomedicine in particular is currently experiencing a revolution caused by the rapid and extraordinary technological leaps in molecular and cellular biology. Powerful high-throughput technologies for DNA/RNA sequencing, mass spectrometry-based proteomics, genome-editing techniques and protein imaging now enable unprecedented understanding of the molecular basis of human disease.

Translating this knowledge into new clinical procedures and treatments demands a deeper understanding of disease-related proteins and their function.

Proteins are the main effectors of cellular function. Their myriad functions include safeguarding the stability of our genome, being the structural and enzymatic components of the cell, and serving as cell-surface receptors and growth factors that mediate cell and tissue communication.

Detailed mechanistic studies of how genetic alterations affect protein function, how proteins interact within signaling pathways to affect cell behavior, and how post-translational modifications such as phosphorylation and ubiquitylation serve to regulate disease signaling pathways will contribute to the progress of translational research within medicine and provide important insights may be used in developing new treatment modalities.

Designed to appeal to both clinical and basic scientists, the course brings together a group of experienced researchers and teachers to provide a comprehensive, theoretical and practical training in the application of state-of-the-art techniques in cellular and molecular biology characterizing protein mechanisms of action in living cells. 

The course is organized by faculty the Novo Nordisk Foundation Center for Protein Research ( and will take place at CPR’s state of the art facilities.  

Course structure/ teaching methods

The course is comprised of two modules: an e-learning module with online lectures, theoretical exercises and literature reviews and a classroom learning module lasting two weeks mainly with student-led seminars, lab exercises and demonstrations.

Lecturers: A variety of international and national professors teach this course. You will get a feeling of a true international classroom.

Credits: 5 ECTS

Course participation, written assignment, 96 hours essay

Marking scale: pass/fail


Medical, dentistry, veterinary, pharmacist, molecular biomedicine and basic science graduates with a BSc degree in any biological science or chemistry are eligible to apply.

This MSc level course will provide excellent training in several general areas of protein research including mass spectrometry based methods for quantitative analysis of proteins and post-translational modifications, light microscopy-based analysis of protein signaling and protein-protein interactions, gene editing, and the use of immunological and genetic methods for analyzing chromatin-associated proteins.

The skills acquired in the course will be targeted to students aiming at a career in scientific research but also useful to those wishing to pursue a career in industry, clinical service or related disciplines.

You must be able to read and write English at a scientific level.

Application procedures

The online application form will be available on this web page 22 January 2018. The application deadline is 1 April 2018.

Tuition fee

Participants exempted from payment:

Students from Danish universities will not be charged any tuition fee provided that the course is accepted as part of their MSc programme. Danish students must provide a pre-approval of credit transfer upon application.

Students enrolled in certain programmes at the Faculty of Health and Medical Sciences, UCPH, do not need a pre-approval of credit transfer. Please study the overview of study programmes, where preapproval of summer course is not required.

Exchange students from the Faculty of Health and Medical Sciences', UCPH, partner universities can participate in this course free of charge, if they have been nominated by their home university. The course must be an integrated part of their study programme.

Fee paying participants:

All other participants (students, working professionals, etc.) must pay tuition fee according to the information below.

EU/EEA citizens: 5,000 DKK
Non-EU/EEA citizens: 9,000 DKK

The fee covers participation in the course. It does not cover course materials, travel, accommodation and living expenses during the course. Full payment of course fees must be transferred in May 2018. Payment details will be forwarded upon acceptance.

Refund policy

You can only get a refund of your tuition fee, if you cancel at least two month prior to the beginning of the course including e-learning modules.

Contact information

Course administration: Marie Sofie Yoo Larsen

Course responsible: Jesper Velgaard Olsen

The course is organized by faculty and the Novo Nordisk Foundation Center for Protein Research (CPR). It will take place at the CPR’s state of the art facilities at the Faculty of Health and Medical Sciences.

Additional Information

Accommodation: Please note that the summer courses are non-residential. Participants are responsible for finding and funding accommodation during their stay in Copenhagen.

You can use different online portals to search for accommodation, such as:

Copenhagen has an international airport, and the city centre can be reached within 30 minutes. If you want additional information read Arriving in Copenhagen.

For more details about the course, please read the course description in UCPH's course database.

For more information about Faculty of Health and Medical Sciences at the University of Copenhagen.