Interactions of nanoparticles with physiological fluids

DRA symposium

Nanoparticles (NPs) are increasingly being explored for their potential applications in the field of disease diagnosis, drug delivery, and targeted therapy. When introduced into the physiological environment, NPs inevitably interact with the biomolecules in the body fluids and the interactions were found of great importance in determining the fate of NPs. This symposium will cover different NPs and physiological fluids, the methods to study the interactions, and the influence on drug delivery outcome.

Programme

14:25

Introduction – Jun Cai and Ben Boyd
14:30

Nanoparticles in biological systems
Rene Holm, Professor, Department of Physics, Chemistry and Pharmacy, University of Southern Denmark
14:50

Student talk from LEO group
Emilie Marie Nielsen (The interplay between host defence peptides and bacterial membrane vesicles during infection)
15:05

Student talk from PP group
Ziwei Yu (title tbc)
15:20 

Excipients influence nanoparticle diffusion in intestinal mucus
Hanne Mørck Nielsen, Professor, Department of Pharmacy, University of Copenhagen, Denmark
15:40 

Coffee Break and Networking
16:00 

Characterization of nanoparticles and proteins using asymmetric flow field-flow fractionation (AF4)
Lars Nilsson, Professor, Division of Food and Pharma, Lund University, Sweden
16:20

Student talk from LEO group
Camilla Jantzen Asgreen (Lyotropic liquid crystalline nanoparticles and their biological consequences during skin infections)
16:35

Student talk from SBI group
Qianying Chen (Formation of gastrointestinal corona on lipid mesophase particles)
16:50

In vitro models for predicting the blood biomolecular corona of nanoparticles in physiological conditions
Francesca Baldelli Bombelli, Associate Professor, Department of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Italy
17:10

Concluding remarks

The symposium is organized on behalf of the graduate programme in pharmaceutical sciences, Drug Research Academy, by Jun Cai and Ben Boyd, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen.

The symposium is free of charge and open for attendance by all interested parties. It is not necessary to pre-register.